Alopexy 5% Minoxidil Pierre Fabre
3 x Months Treatment ( 3 x 60ml )
ALOPEXY 5% was developed specifically for hair loss.
Minoxidil is one of the active ingredients used as a topical medication.
There is ample medical and scientific evidence on the effectiveness of minoxidil on hair loss.
In fact, minoxidil stops the fall of the hair and stimulates the regrowth of the hair throughout the duration of the treatment.
The results are visible after 4 months of treatment.
This medicine is used in certain moderate cases of so-called androgenetic alopecia (excessive hair loss) in men.
This medicine is not recommended for use in women, as abnormal hair growth (hypertrichosis) is often expected.
Active ingredients:
50 mg lidocaine;
Ethanol 96% (V / V) excipient (+).
Propylene Glycol Excipient (+).
Water, cleaning aid (+).
Contraindications:
The medicinal product must not be used
if you are allergic (hypersensitive) to ferrous sulphate or any of the other ingredients.
If you have already experienced a reaction, indicating an intolerance to the 2% minoxidil solution.
If you have a condition or injury to the scalp.
Children and elderly people:
Data on safety and effectiveness for use in children and adolescents under 18 years and over 65 years is not available.
Dosage:
Always use the solution precisely according to the instructions. Please ask your doctor or pharmacist if you are not too sure.
As a normal dose, 1 ml is applied twice daily to the scalp surface to be treated.
The daily amount should not exceed 2 ml.
Features:
Quantity: 3x Bottles x 60 ml.
Men’s medicine against hair loss.
Improves the nutrient supply to the hair root.
For risks and side effects, read the package leaflet (English language not guaranteed) and consult your doctor or pharmacist.
Ingredients:
Active ingredient:Minoxidil
Directions:
Adult men over the age of 18 apply 1 ml twice a day to the affected areas of the scalp, starting in the center of the affected area. The specified amount, regardless of the size of the area to be treated, must be adhered to. The total dose should not exceed 2 ml
Legal disclaimer
Ask your doctor or pharmacist about risks and side effects.
Clinically proven efficacy :
Alopexy stimulates hair growth in persons with early and moderate stages of hereditary hair loss (alopecia androgenetica).
This hair loss appears in men as a receding hairline and balding in the vertex area.
The exact mechanism of action of minoxidil for topical treatment of alopecia is not fully understood, but Alopexy 5% can reverse the hair loss process of androgenetic alopecia by the following means:
– Increasing the diameter of the hair shaft
– Stimulating anagen growth
– Prolonging the anagen phase
– Stimulating anagen recovery from the telegen phase
As a peripheral vasodilator Alopexy enhances microcirculation to hair follicles. The Vascular Endothelial Growth Factor (VEGF) is stimulated by Alopexy and VEGF is presumably responsible for the increased capillary fenestration, indicative of a high metabolic activity, observed during the anagen phase.
The efficacy of Alopexy 5% has been assessed in a Phase 3 clinical trial conducted over a 16-week treatment period. In this study Alopexy 5% was compared to the product vehicle without the minoxidil active ingredient.
The primary efficacy endpoints were a) mean change in non-vellus hair count within the target region between Baseline and Week 16, as determined by validated computer-assisted dot-mapping technique; and b) subject rating of treatment benefit via use of global photographs of the vertex region, assessed as an overall improvement from baseline, collected on a subject questionnaire.
The active treatment showed a statistically significant greater increase in hair count than the vehicle foam group (21.0 versus 4.3 hairs cm2) at week 16. A clear difference between treatment groups was already evident at week 8, increasing at week 12 and again at week 16. The subject`s rating of treatment benefit was statistically significantly better for the Alopexy 5% treatment group than placebo (1.4 vs 0.5) at week 16.
The secondary efficacy endpoints were a) expert panel review (EPR) of hair regrowth when comparing global photographs obtained at baseline with photographs obtained at Week 16 and b) percent change from baseline in non-vellus hair counts within a pre-specified area of clipped hair.
The Alopexy 5% group showed a better score in the expert panel review (EPR) than the placebo foam group (adjusted mean 0.5 vs 0.1, p<0.0001). At weeks 8, 12 and 16, the difference in adjusted means for percent change in non-vellus hair counts between vehicle foam and Alopexy 5% were statistically significant (p<0.0001 at all 3 visits). Alopexy Data: Mean change in non-vellus hair count in reference 1cm2 area of scalp compared with baseline. The systemic absorption of minoxidil from Alopexy 5% formulation has been estimated in a pharmacokinetic study in subjects with androgenetic alopecia, which included 5% minoxidil foam as a comparator. This demonstrated that in men, the systemic absorption of minoxidil from twice daily application of 5% minoxidil foam was about half of that observed with Alopexy 5% minoxidil solution.
Angelina –
I decided to wait before i wrote a review. I bought the treatment for 3x months .
After about 2 months in you start noticing a difference , but you will really see results in about 3 months and so on.
Initially i went through the shed period that others have noted and it was a little scary. However, all of that hair has grown back in and I now have good coverage in the recessions and along the hairline.
I’m pleased with the results i get after 3 months and now i will continue using it ,because it just works !